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Risk of Endocarditis for Cardiac Conditions
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American Heart Association Website
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HIGH RISK (PROPHYLAXIS RECOMMENDED)MEDIUM RISK (PROPHYLAXIS RECOMMENDED)NEGLIGIBLE RISK (PROPHYLAXIS NOT RECOMMENDED)
Prosthetic cardiac valves, including bioprosthetic and homograft valvesMost congenital cardiac malformations that are not high or negligible riskIsolated secundum atrial septal defect
Previous bacterial endocarditisAcquired valvar dysfunction (eg, rheumatic heart disease)Surgical repair of atrial septal defect, ventricular septal defect, or patent ductus arteriosus (without residua beyond 6 mo)
Complex cyanotic congenital heart disease (eg, single ventricle states, transposition of the great arteries, tetralogy of Fallot)Hypertrophic cardiomyopathyPrevious coronary artery bypass graft surgery
Surgically constructed systemic pulmonary shunts or conduitsMitral valve prolapse with valvar regurgitation and/or thickened leaflets Mitral valve prolapse without valvar regurgitation
Physiologic, functional, or innocent heart murmurs
Previous Kawasaki disease without valvar dysfunction
Previous rheumatic fever without valvar dysfunction
Cardiac pacemakers (intravascular and epicardial) and implanted defibrillators

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